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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
sensitisation data (humans)
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
other: OECD SIDS
Rationale for reliability incl. deficiencies:
other: OECD SIDS

Data source

Reference
Reference Type:
other: SIDS initial assessment report
Title:
SIDS Initial Assessment Report for SIAM 19, 4-Aminodiphenylamine (4-ADPA)
Author:
OECD SIDS
Year:
2004
Bibliographic source:
OECD SIDS, SIDS Initial Assessment Report

Materials and methods

Type of sensitisation studied:
skin
Study type:
other: review OECD SIDS
Principles of method if other than guideline:
review

Test material

Constituent 1
Chemical structure
Reference substance name:
N-(4-aminophenyl)aniline
EC Number:
202-951-9
EC Name:
N-(4-aminophenyl)aniline
Cas Number:
101-54-2
Molecular formula:
C12H12N2
IUPAC Name:
N1-phenylbenzene-1,4-diamine
Details on test material:
4-ADPA

Method

Route of administration:
dermal

Results and discussion

Results of examinations:
review: skin sensitzing data (human patch testing studies from a wide range of dermatology patients)

Applicant's summary and conclusion