Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
partition coefficient
Type of information:
calculation (if not (Q)SAR)
Remarks:
Migrated phrase: estimated by calculation
Adequacy of study:
supporting study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Internationally accepted method, EPI-Suite EPA (USA)

Data source

Reference
Reference Type:
other: estimated by calculation
Title:
Unnamed
Year:
2013

Materials and methods

Principles of method if other than guideline:
EPI-Suite KOWWIN v1.68 estimate
GLP compliance:
no
Type of method:
other: estimated by calculation
Partition coefficient type:
octanol-water

Test material

Constituent 1
Chemical structure
Reference substance name:
Erythromycin thiocyanate
EC Number:
231-723-1
EC Name:
Erythromycin thiocyanate
Cas Number:
7704-67-8
Molecular formula:
C37H67NO13.CHNS
IUPAC Name:
(3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-6-{[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy}-14-ethyl-7,12,13-trihydroxy-4-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy}-3,5,7,9,11,13-hexamethyl-1-oxacyclotetradecane-2,10-dione; sulfanylformonitrile

Results and discussion

Partition coefficient
Type:
log Pow
Partition coefficient:
2.37
Remarks on result:
other: log Kow (KOWWIN v1.68 estimate). No data is provided on temperature and pH.

Applicant's summary and conclusion

Conclusions:
Log Pow EPISUITE = 2.37 (KOWWIN v1.68 estimate)
Executive summary:

Log Pow EPISUITE = 2.37 (KOWWIN v1.68 estimate)