Registration Dossier
Registration Dossier
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EC number: 269-915-2 | CAS number: 68390-97-6 This substance is identified by SDA Substance Name: C16-C18 alkyl dimethyl amine and SDA Reporting Number: 19-040-00.
Acute Toxicity: oral
Administrative data
- Endpoint:
- acute toxicity: oral
- Type of information:
- read-across based on grouping of substances (category approach)
- Adequacy of study:
- key study
- Justification for type of information:
- For details on endpoint-specific justification, please see read-across justification document (category approach) in the linked category of dimethylalkylamines.
Data source
Materials and methods
- GLP compliance:
- yes
Test material
- Reference substance name:
- Amines, C16-18-alkyldimethyl
- EC Number:
- 269-915-2
- EC Name:
- Amines, C16-18-alkyldimethyl
- Cas Number:
- 68390-97-6
- Molecular formula:
- R-N(Me)2, whereas R= C16-18-alkyl (even numbered, unbranched, saturated)
- IUPAC Name:
- N,N-dimethyl-C16-18-(even numbered)-alkyl-1-amines
Constituent 1
Results and discussion
Effect levels
- Sex:
- male/female
- Dose descriptor:
- LD50
- Effect level:
- 1 085 mg/kg bw
- Based on:
- other: Read-across from C16-DMA; value converted based on MW
- Remarks on result:
- other: Original data for the source: 1015 mg/kg bw
Applicant's summary and conclusion
- Executive summary:
The study used as source investigated the acute oral toxicity of C16-DMA. The study results of the source compound were considered applicable to the target compound. Justification and applicability of the read-across approach (category approach) is outlined in the read-across report in the linked category of dimethylalkylamines.
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