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EC number: 232-088-3
CAS number: 7785-84-4
Clinical Observations and Mortality Data
Dose Level mg/kg
Animal Number and Sex
Effects Noted After Dosing(Hours)
Effects Noted During Period After Dosing(Days)
Bodyweights and Bodyweight Changes
Bodyweight (g) at Day
Bodyweight Gain (g) During Week
Animal Numberand Sex
Time of Death
Killed Day 14
No abnormalities detected
No signs of systemic toxicity
study was performed to assess the acute oral toxicity of the test
material in the Wistar strain rat. The method was designed to meet the
requirements of the following:
Guidelines for Testing of Chemicals No 420 “Acute Oral Toxicity - Fixed
Dose Method” (adopted 17 December 2001)
B1 bis Acute Toxicity (Oral) of Commission Regulation (EC) No. 440/2008
a sighting test at a dose level of 2000 mg/kg, an additional four fasted
female animals were given a single oral dose of test material, as a
suspension in distilled water, at a dose level of 2000 mg/kg
bodyweight. Clinical signs and bodyweight development were monitored
during the study. All animals were subjected to gross necropsy.
were no deaths.
were no signs of systemic toxicity.
animals showed expected gains in bodyweight.
abnormalities were noted at necropsy.
acute oral median lethal dose (LD50) of the test material in
the female Wistar strain rat was estimated to be greater than 2000 mg/kg
bodyweight (Globally Harmonised Classification System-Unclassified).
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