Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 232-088-3
CAS number: 7785-84-4
To study metabolism and urinary
excretion of sodium trimetaphosphate, sodium tripolyphosphate, and
sodium hexaphosphate, these substances were administered to rabbits.
Subsequently, animals were placed in metabolic cages, blood and urine
samples were obtained and analysed on orthophosphates and
acid-hydrolysable phosphates called ‘labile phosphates’.
After intravenous injection of 249
mg/kg bw trisodium trimetaphosphate into rabbits, plasma concentration
of polymeric (‘labile’) phosphate declined almost exponentially. At best
a slight increase in serum orthophosphate concentration (resulting from
metaphosphate hydrolysis) was visible. Urinary excretion followed the
decline in serum phosphate quite well, the vast majority of
metaphosphate was excreted unhydrolysed. Alltogether, about 60% of the
administered dose was excreted in urine within 3h.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
Questo sito web si avvale di cookie affinché possiate usufruire della migliore esperienza sui nostri siti web.
Welcome to the ECHA website. This site is not fully supported in Internet Explorer 7 (and earlier versions). Please upgrade your Internet Explorer to a newer version.
Do not show this message again