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EC number: 200-073-0
CAS number: 50-97-5
Table 1: Number of animals dead (and with evident
(# dead / total)
Time range of deaths
Number with evident toxicity
(# / total)
Table 2. Systemic Observation
No entry indicates animal appeared normal at that observation period.
= Hair loss: left side of the neck 2 = Partially chewed food on pan
liner F = Piloerection S = Chromorhinorrhea X = Few feces
OECD 425 (2017) - In an acute oral toxicity study, a group of fasted,
8-12 week old female Wistar rats were given a single oral dose of
TX16352 at a single dose rate of 2000 mg/kg bw (limit test) and observed
for 14 days.
In the absence of mortality during the observation period, the oral LD50
was estimated to be greater than 2000 mg/kg bw.
In addition, there were no treatment related clinical signs, necropsy
findings or changes in body weight observed in any of the individuals.
In conclusion, the test item, TX16352 did not meet the criteria for
classification according to Regulation (EC) No. 1272/2008 on the
Classification, Labelling and Packaging of Substances and Mixture.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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