Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Endpoint summary

Administrative data

Description of key information

Additional information

For the assessment of the aquatic toxicity of Hexamethylene diisocyanate, trimers, reaction products with 2-hydroxyethyl acrylate (CAS 162492-01-5), experimental studies are available, which cover the short-term toxicity to all three trophic levels (fish, aquatic invertebrates and algae) and the long-term toxicity to one trophic level (aquatic algae). All studies were performed according to the internationally accepted OECD guidelines and GLP. Neither acute (fish, aquatic invertebrates and algae) nor chronic toxicity (algae) was recorded up to the limit of water solubility. Moreover, the toxicity control of a standard ready biodegradability test indicates no toxic effects on activated sludge microorganisms.