Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 203-856-5 | CAS number: 111-30-8
Toxicity to soil macroorganisms except arthropods
Administrative data
Link to relevant study record(s)
Description of key information
glutaraldehyde revealed very low acute toxicity to earthworm indicated by a LC50 value of 170 mg a.i./kg dry weight soil. The result converted to wet weight by dividing with a factor of 1.13 (EUSES manual) results in a LC50 of 150 mg a.i./kg ww.
Key value for chemical safety assessment
- Short-term EC50 or LC50 for soil macroorganisms:
- 170 mg/kg soil dw
Additional information
The acute toxicity of glutaraldehyde 50% to earthworms was studied with Eisenia
foetida according to OECD Guideline 207 (BASF AG
01/0411/67/1). Adult earthworms (with visible clitella) were
exposed for 14 days to glutaraldehyde-treated artificial soil. The
nominal test concentrations were 0, 62.5, 125, 250, 500 and 1000 mg/kg
dry weight soil. The animals were checked after 7 and 14 days for
mortality, behaviour and body weight. Test substance-related
mortality was observed at the two highest tested concentrations of 500
(15%) and 1000 mg/kg soil (25%); at 250 mg/kg soil, no mortality was
observed. The LC50 was 170 mg a.i./kg soil.
In conclusion, glutaraldehyde revealed very low acute toxicity to
earthworm. Nevertheless, for a substance being considered as „readily
biodegradable“, it can be assumed that it will be biodegraded within the
STP process and as a consequence a transfer to the soil compartment is
not expected. In addition, the substance is not bioaccumulative.
Therefore, toxicity to soil macroorganisms is unlikely.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
