Registration Dossier
Registration Dossier
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EC number: 228-528-9 | CAS number: 6289-46-9
Toxicity to microorganisms
Administrative data
- Endpoint:
- activated sludge respiration inhibition testing
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Study period:
- 1989
- Reliability:
- 2 (reliable with restrictions)
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 989
- Report date:
- 1989
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 209 (Activated Sludge, Respiration Inhibition Test
- Deviations:
- not specified
- GLP compliance:
- not specified
Test material
- Reference substance name:
- Dimethyl 2,5-dioxocyclohexane-1,4-dicarboxylate
- EC Number:
- 228-528-9
- EC Name:
- Dimethyl 2,5-dioxocyclohexane-1,4-dicarboxylate
- Cas Number:
- 6289-46-9
- Molecular formula:
- C10H12O6
- IUPAC Name:
- 1,4-dimethyl 2,5-dioxocyclohexane-1,4-dicarboxylate
Constituent 1
Sampling and analysis
- Analytical monitoring:
- not specified
Test solutions
- Vehicle:
- no
Test organisms
- Test organisms (species):
- activated sludge of a predominantly domestic sewage
Study design
- Test type:
- static
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 3 h
Test conditions
- pH:
- 7.6
- Reference substance (positive control):
- yes
- Remarks:
- 3,5-Dichlorophenol
Results and discussion
Effect concentrations
- Duration:
- 3 h
- Dose descriptor:
- EC50
- Effect conc.:
- > 1 000 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- other: respiration inhibition
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Executive summary:
The results of testing this substance according to OECD 209 (activated sludge repsiration inhibition) revealed that the EC50 of this substance is higher than 1000 mg/L
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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