Registration Dossier
Registration Dossier
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EC number: 201-607-5 | CAS number: 85-44-9
Endpoint summary
Administrative data
Description of key information
Additional information
Assessing the bioaccumulation potential in aquatic organisms, a BCF has been calculated with the BCF Program (v 3.01)
taking the octanol-water partition coefficient in account. Using the log KOW of 1.6 for phthalic anhydride, the calculated BCF is 5.3 (Heilkenbrinker, 2017a). For the hydrolysis product phthalic acid, a BCF value of 3.2 is calculated by using the log KOW of 0.73 (Heilkenbrinker, 2017b). These results indicate no significant potential for bioaccumulation of phthalic anhydride and phthalic acid in aquatic organisms.
In green house studies 14C-phthalic acid was applied to soil planted with wheat (Triticum aestivum)/corn (Zea mays) or soybeans (Glycine max)/tall fescue (Festuca arundinacea). For phthalic acid the bioaccumulation ratios were 0.013 for plants and 0.0046 for seeds. TLC analysis showed that the percent of the extractable 14C still in phthalic acid, was 5 % in corn and fescue, 15 % in soybean, 9 % in wheat plants, and the highest for wheat seed (47 %) (Dorney, 1985). This study demonstrates the relatively low potential for accumulation of phthalic acid in plants.
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