Registration Dossier
Registration Dossier
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EC number: 240-383-3 | CAS number: 16291-96-6 An amorphous form of carbon produced by partially burning or oxidizing wood or other organic matter.
Endpoint summary
Administrative data
Link to relevant study record(s)
Description of key information
Key value for chemical safety assessment
Additional information
At present, it is not expected that charcoal becomes systemically available at significant amounts as in the granulometry studies performed with three representative charcoal samples only a minor fraction was inhalable (particle sizes ≤ 100 µm) and more importantly only a negligible fraction was respirable (particle sizes ≤ 2 µm). In addition, there is no evidence for a significant translocation of even smaller carbonaceous particles (35 nm) to the systemic circulation upon inhalation (Wiebert et al. 2006). However, as toxicokinetic data might be decisive for further testing, a pharmacokinetic study according to OECD TG 417 is recommended.
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