Registration Dossier
Registration Dossier
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EC number: 448-050-6 | CAS number: 444065-11-6
Endpoint summary
Administrative data
Description of key information
Additional information
Acute tests evaluating the toxicity of 2-(4-tert-butylphenyl)-6-cyano-5-[bis(ethoxycarbonylmethyl)carbamoyloxy]-1 H-pyrrolo[1 ,2-b][1 ,2,4]triazole-7-carboxylic acid-2,6-di-tert-butyl-4-methyl-cyclohexyl ester (UC-141) to aquatic organisms from three different trophic levels are available. The substance did not cause any adverse effects on fish survival (LC50 (96 h) > 0.015 mg/L, measured), aquatic invertebrates mobility (EC50 (48 h)> 0.019 mg/L, measured) or algal growth (EC50 (72 h) > 0.01 mg/L, measured). Also, no adverse effects were observed on the activity of activated sludge microorganisms after 30 minutes of exposure, leading to an EC50 > 100 mg/L (nominal). This result is supported by the results of the toxicity control in the biodegradation test (see IUCLID section 5.2.1) which showed that UC-141 is not inhibitory to aquatic microorganisms (> 25% biodegradation within 14 days).
Based on the available information, UC-141 is considered to be not acutely toxic to aquatic organisms up to the highest attainable concentrations in test media.
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