Registration Dossier
Registration Dossier
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EC number: 206-735-5 | CAS number: 371-40-4
Toxicity to soil macroorganisms except arthropods
Administrative data
- Endpoint:
- toxicity to soil macroorganisms except arthropods: short-term
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
Data source
Reference
- Reference Type:
- review article or handbook
- Title:
- Reaxys ID : 742030
- Year:
- 2 011
- Bibliographic source:
- Reaxys by Elsevier Properties SA; Ji, Li; Bundy, Jacob G.; Lenz, Eva M.; Bailey, Nigel J.; et al. ; Environmental Toxicology and Chemistry; vol. 21; nb. 9; (2002); p. 1966 - 1972
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other:
- Principles of method if other than guideline:
- Rapid toxicity test (Organization for Economic and Development):Test material in hexane was applied to the filter paper (52 cm2) and allowed to evaporate; moistened with 1 ml of water; single earthworm placed on to the filter and incubated for 72 h
- GLP compliance:
- not specified
Test material
- Reference substance name:
- 4-fluoroaniline
- EC Number:
- 206-735-5
- EC Name:
- 4-fluoroaniline
- Cas Number:
- 371-40-4
- Molecular formula:
- C6H6FN
- IUPAC Name:
- 4-fluoroaniline
- Details on test material:
- - Name of test material: 4-fluoroaniline
- Molecular formula: C6H6FN
- Molecular weight: 111.12
- Substance type: Organic
- Physical state: Liquid
Constituent 1
Sampling and analysis
- Analytical monitoring:
- not specified
Test substrate
- Vehicle:
- not specified
Test organisms
- Test organisms (species):
- Eisenia sp.
- Animal group:
- annelids
- Details on test organisms:
- Test organism: Eisenia veneta, earthworm
Study design
- Study type:
- laboratory study
- Substrate type:
- filter paper
- Total exposure duration:
- 72 h
Test conditions
- Details on test conditions:
- Test material in hexane was applied to the filter paper (52 cm2) and allowed to evaporate; moistened with 1 ml of water; single earthworm placed on to the filter and incubated for 72 h
- Nominal and measured concentrations:
- 25 - 250 μg/cm2
Results and discussion
Effect concentrations
- Duration:
- 72 h
- Dose descriptor:
- LC50
- Effect conc.:
- 115 other: μg/cm2
- Nominal / measured:
- meas. (not specified)
- Conc. based on:
- test mat.
- Basis for effect:
- mortality
Applicant's summary and conclusion
- Conclusions:
- The LC50 (median lethal concentration) value of 4-fluoroaniline to Eisenia veneta (earthworm) during a 72 hr exposure is 115 μg/cm2.
- Executive summary:
The LC50 (median lethal concentration) value of 4-fluoroaniline to Eisenia veneta (earthworm) during a 72 hr exposure is 115 μg/cm2.
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