Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 608-929-9
CAS number: 33955-44-1
An acute oral toxicity following OECD guideline 4223 and in compliance
with GLP was performed to assess the test article's acute oral toxicity
in Wistar rats. A single dose of 2000 mg/kg body weight of the test
material preparation in 0.5 % Tylose CB 30.000 in Aqua bidest. was given
to six fasted animals (three males and three females) by gavage in
sequential manner. No mortality occurred. No signs of toxicity were
observed in the male animals. Signs of toxicity noted in the 2,000 mg/kg
dose group in the female animals comprised impaired and poor general
state, dyspnoea, apathy, staggering, ataxia and piloerection. Findings
were observed from 2 hours after application until including study day
3. The animals gained weight throughout the study period. No
abnormalities were noted at necropsy of the animals at the end of the
study. Under the conditions of this study the median lethal dose of the
test substance after oral application was found to be greater than 2000
mg/kg body weight for the male and female animals.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
Ce site web utilise des cookies afin de vous garantir la meilleure expérience possible sur nos sites web.
Welcome to the ECHA website. This site is not fully supported in Internet Explorer 7 (and earlier versions). Please upgrade your Internet Explorer to a newer version.
Do not show this message again