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EC number: - | CAS number: -
Particle size distribution (Granulometry)
Administrative data
Link to relevant study record(s)
- Endpoint:
- particle size distribution (granulometry)
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- comparable to guideline study with acceptable restrictions
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- OECD Guideline 110 (Particle Size Distribution / Fibre Length and Diameter Distributions - Method A: Particle Size Distribution (effective hydrodynamic radius)
- GLP compliance:
- no
- Type of method:
- Laser scattering/diffraction
- Type of distribution:
- volumetric distribution
- Percentile:
- D10
- Mean:
- 5.764 µm
- Remarks on result:
- other: no St. dev. available
- Percentile:
- D50
- Mean:
- 11.924 µm
- Remarks on result:
- other: no St. dev. available
- Percentile:
- D90
- Mean:
- 22.335 µm
- Remarks on result:
- other: no St. dev. available
- Size:
- < 3 µm
- Distribution:
- 2.27 %
- Remarks on result:
- other: Cumulative passing of specific particle sizes
- Size:
- < 4 µm
- Distribution:
- 3.9 %
- Remarks on result:
- other: Cumulative passing of specific particle sizes
- Size:
- < 10 µm
- Distribution:
- 37.6 %
- Remarks on result:
- other: Cumulative passing of specific particle sizes
- Size:
- < 100 µm
- Distribution:
- 100 %
- Remarks on result:
- other: Cumulative passing of specific particle sizes
- Endpoint:
- particle size distribution (granulometry)
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- comparable to guideline study with acceptable restrictions
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- OECD Guideline 110 (Particle Size Distribution / Fibre Length and Diameter Distributions - Method A: Particle Size Distribution (effective hydrodynamic radius)
- GLP compliance:
- no
- Type of method:
- Laser scattering/diffraction
- Type of distribution:
- volumetric distribution
- Percentile:
- D10
- Mean:
- 5.95 µm
- Remarks on result:
- other: no St. dev. available
- Percentile:
- D50
- Mean:
- 12.3 µm
- Remarks on result:
- other: no St. dev. available
- Percentile:
- D90
- Mean:
- 21.7 µm
- Remarks on result:
- other: no St. dev. available
- Percentile:
- D99
- Mean:
- 30.1 µm
- Remarks on result:
- other: no St. dev. available
- Size:
- < 4 µm
- Distribution:
- 4.4 %
- Remarks on result:
- other: Cumulative passing of specific particle sizes
- Size:
- < 10 µm
- Distribution:
- 38.6 %
- Remarks on result:
- other: Cumulative passing of specific particle sizes
- Size:
- < 100 µm
- Distribution:
- 100 %
- Remarks on result:
- other: Cumulative passing of specific particle sizes
- Endpoint:
- particle size distribution (granulometry)
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 110 (Particle Size Distribution / Fibre Length and Diameter Distributions - Method A: Particle Size Distribution (effective hydrodynamic radius)
- Qualifier:
- according to guideline
- Guideline:
- ISO 13320 (Particle size analysis - Laser diffraction methods)
- Qualifier:
- according to guideline
- Guideline:
- EPA OPPTS 830.7520 (Particle Size, Fiber Length, and Diameter Distribution)
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- Laser scattering/diffraction
- Type of distribution:
- volumetric distribution
- Key result
- Percentile:
- D10
- Mean:
- 5 µm
- St. dev.:
- 0.1
- Key result
- Percentile:
- D50
- Mean:
- 9.7 µm
- St. dev.:
- 0.1
- Key result
- Percentile:
- D90
- Mean:
- 17.1 µm
- St. dev.:
- 0.1
- Size:
- 1 µm
- Distribution:
- 2.19 %
- Remarks on result:
- other: Cumulative passing of specific particle sizes
- Size:
- 2 µm
- Distribution:
- 3.24 %
- Remarks on result:
- other: Cumulative passing of specific particle sizes
- Size:
- 4 µm
- Distribution:
- 5.33 %
- Remarks on result:
- other: Cumulative passing of specific particle sizes
- Size:
- 10 µm
- Distribution:
- 52.51 %
- Remarks on result:
- other: Cumulative passing of specific particle sizes
- Size:
- 20 µm
- Distribution:
- 95.85 %
- Remarks on result:
- other: Cumulative passing of specific particle sizes
- Size:
- 25 µm
- Distribution:
- 99.74 %
- Remarks on result:
- other: Cumulative passing of specific particle sizes
- Size:
- 50 µm
- Distribution:
- 100 %
- Remarks on result:
- other: Cumulative passing of specific particle sizes
Referenceopen allclose all
Results
Latitude: 1.279
Uniformity: 0.398
Dv (10): 5.95 μm
Dv (50): 12.3 μm
Dv (90): 21.7 μm
Dv (99): 30.1 μm
Laser isolation: 7.84%
Laser power: 75.49%
Specific surface: 634.8 m²/kg
Weighted deviation: 0.23 %
D [3;2]: 7.11 μm
D [4;3]: 13.1 μm
Concentration: 0.0077 %
Mode Count: 1
Calibration detector: Type RCNL
Has record been changed?: No
Sample Information: < 32 μm
Particle Size Distribution
Two test series of 3 measurements each were performed with the test item.
The test item shows a mono-modal particle size distribution.
Test series 1 | ||
D10 | 5.02 µm | Standard deviation: 0.02 µm |
D50 | 9.69 µm (Median diameter) | Standard deviation: 0.06 µm |
D90 | 17.04 µm | Standard deviation: 0.11 µm |
Test series 2 | ||
D10 | 5.02 µm | Standard deviation: 0.01 µm |
D50 | 9.71 µm (Median diameter) | Standard deviation: 0.03 µm |
D90 | 17.11 µm | Standard deviation: 0.05 µm |
Average | ||
D10 | 5.0 µm | Standard deviation: < 0.1 µm |
D50 | 9.7 µm (Median diameter) | Standard deviation: < 0.1 µm |
D90 | 17.1 µm | Standard deviation: < 0.1 µm |
Cumulative passing of specific particle sizes:
Particle size / µm | Passing / % | Passing / % | Passing / % |
1 | 2.18 | 2.20 | 2.19 |
2 | 3.23 | 3.25 | 3.24 |
4 | 5.32 | 5.34 | 5.33 |
10 | 52.60 | 52.42 | 52.51 |
20 | 95.91 | 95.78 | 95.85 |
25 | 99.76 | 99.71 | 99.74 |
50 | 100.00 | 100.00 | 100.00 |
Description of key information
The particle size distribution of the substance is determined to be
D10: 3.4 µm D50: 8.9 µm D90: 14.8 µm for form 1 of the substance
The cumulative passing of specific particle sizes are
<100 µm: 100 % <10 µm: 60.06 % <4 µm: 11.43 % for form 1 of the substance
D10: 5.0 µm D50: 9.7 µm D90: 17.1 µm for form 4 of the substance
The cumulative passing of specific particle sizes are
<100 µm: 100 % <10 µm: 52.51 % <4 µm: 5.33 % for form 4 of the substance
D10: 5.8 µm D50: 11.9 µm D90: 22.3 µm for form 2 of the substance
D10: 5.9 µm D50: 12.3 µm D90: 21.7 µm for form 3 of the substance
Additional information
The particle size distributions of the individual forms of the set of similar nanoforms were determined.
Two GLP studies were conducted in accordance with OECD Guideline for the Testing of Chemicals 110 using the Laser diffraction method according to ISO 13320.
The results were as follows:
D10: 3.4 µm D50: 8.9 µm D90: 14.8 µm for form 1 of the substance
The cumulative passing of specific particle sizes are
<100 µm: 100 % <10 µm: 60.06 % <4 µm: 11.43 % for form 1 of the substance
D10: 5.0 µm D50: 9.7 µm D90: 17.1 µm for form 4 of the substance
The cumulative passing of specific particle sizes are
<100 µm: 100 % <10 µm: 52.51 % <4 µm: 5.33 % for form 4 of the substance
In addition two non-GLP studies were conducted equivalent or similar with OECD Guideline for the Testing of Chemicals 110 using the Laser diffraction method according to ISO 13320.
The results were as follows:
D10: 5.8 µm D50: 11.9 µm D90: 22.3 µm for form 2 of the substance
D10: 5.9 µm D50: 12.3 µm D90: 21.7 µm for form 3 of the substance
Range of particle size distribution of different nanoforms in the set in the µm SCALE
Particle size | NCM- PCAM form 1 | NCM- PCAM form 2 | NCM- PCAM form 3 | NCM- PCAM form 4 |
D10 | 3.4 µm | 5.8 µm | 5.9 µm | 5 µm |
D50 | 8.9 µm | 11.9 µm | 12.3 µm | 9.7 µm |
D90 | 14.8 µm | 22.3 µm | 21.7 µm | 17.1 µm |
Range of particle size distribution at different passages of different nanoforms in the set in the µm SCALE
Particle size distribution at different passages | NCM- PCAM form 1 | NCM- PCM form 2 | NCM- PCAM form 3 | NCM- PCAM form 4 * |
4 μm | 11.4 % | 3.9 % | 4.4 % | 5.3 % |
10 μm | 60.1 % | 37.6 % | 38.6 % | 52.5 % |
100 μm | 100 % | 100 % | 100 % | 100 % |
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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