2,2,3,3,4,4,5,5-octafluoropentyl methacrylate

Endpoint summary

Description of key information

The assessment of ready biodegradability was performed according to two GLP-complaint studies following OECD Guideline 310. The first study conducted in 2010 determined the OFPMA attained 27% degradation after 28 days and therefore cannot be considered to be readily biodegradable. The second study conducted in 2016 determined the OFPMA attained 22% degradation after 28 days and therefore cannot be considered to be readily biodegradable.

 

The 2016 study included compound analyses with GC/MS on Days 0, 14 and 28 from duplicate test item and inoculum control vessels. The test item (OFPMA) was shown to fairly quickly form the degradant, octafluoropentanol (CAS 355-80-6). It was considered that the test item that did not degrade to octafluoropentanol was suspected to have broken down to form methacrylic acid which was not analytically measured due to the amount formed being below the limit of quantification. The methacrylic acid was considered to have mineralized with carbon dioxide evolution shown by the inorganic carbon analyses. The concentration of the degradant on Day 14 (average of 29.6 mg/L) was similar to the concentration reported on Day 28 (average of 35.2 mg/L). Since the octafluoropentanol did not show evidence of mineralization within the 28-day study, the parent compound cannot be considered to be inherently biodegradable.