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Diss Factsheets

Environmental fate & pathways

Biodegradation in water: screening tests

Administrative data

Endpoint:
biodegradation in water: ready biodegradability
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: study performed according to OECD and GLP guidelines
Cross-referenceopen allclose all
Reason / purpose for cross-reference:
reference to same study
Reason / purpose for cross-reference:
reference to other study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1998
Report date:
1998

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 301 B (Ready Biodegradability: CO2 Evolution Test)
Deviations:
no
GLP compliance:
yes (incl. QA statement)

Test material

Constituent 1
Chemical structure
Reference substance name:
4-hydroxy-2-methylnaphthyl benzoate
EC Number:
218-647-4
EC Name:
4-hydroxy-2-methylnaphthyl benzoate
Cas Number:
2211-28-1
Molecular formula:
C18H14O3
IUPAC Name:
4-hydroxy-2-methyl-1-naphthyl benzoate

Study design

Oxygen conditions:
aerobic
Inoculum or test system:
activated sludge (adaptation not specified)
Duration of test (contact time):
28 d
Initial test substance concentration
Initial conc.:
12 mg/L
Based on:
ThOD/L

Results and discussion

% Degradation
Parameter:
% degradation (CO2 evolution)
Value:
ca. 14
Sampling time:
28 d
Details on results:
not readily biodegradable

Applicant's summary and conclusion

Validity criteria fulfilled:
yes
Interpretation of results:
other: about 14% degradation observed
Conclusions:
The criterion for ready biodegradability (at least 60% degradation within 10 days of biodegradation exceeding 10%) was
not met.
Executive summary:

MONOBENZOATE was tested for its ready biodegradability in the carbon dioxide (C02) evolution test (modified Sturm test) at 31-32 mg per 2 litres, corresponding to 12 mg TOG/l. The study procedure was based on EEC directive 92/69, C.4-C, December 1992, and OECD guideline No. 301 B July 17, 1992. The Theoretical CO2 production (ThC02) of MONOBENZOATE was calculated to be 2.85 mg CO2/mg. The relative degradation values calculated from the measurements performed during the test period revealed 10 and 19% degradation of MONOBENZOATE for A and B respectively. Thus, the criterion for ready biodegradability (at least 60% degradation within 10 days of biodegradation exceeding 10%) was not met. In the toxicity control MONOBENZOATE was found to be not inhibitory. Since all acceptability criteria prescribed by the protocol were met, this study was considered to be valid. In conclusion, MONOBENZOATE was not readily biodegradable under the conditions of the modified Sturm test presently performed.