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EC number: 273-769-5
CAS number: 69012-72-2
Residue from treatment of calcined zinc ore concentrates with antimony trioxide, zinc dust, lead oxide and copper sulfate. Consists primarily of zinc and a composite of metallics: cobalt, copper and lead.
Zinc is an essential element which is actively regulated by organisms, so bioconcentration/bioaccumulation is not considered relevant.
Bioaccumulation is not considered relevant for essential elements
because of the general presence of homeostatic control mechanisms.
McGeer et al (2003) recently extensively the reviewed evidence on
bioconcentration and bioaccumulation of zinc as a function of exposure
concentration in a number of taxonomic groups (algae, molluscs,
arthropods, annelids, salmonid fish, cyprinid fish, and other fish). The
data clearly illustrated that internal zinc content is well regulated.
All eight species taxonomic groups investigated exhibited very slight
increases in whole body concentration over a dramatic increase in
exposure concentration. In fact, most species did not show significant
increases in zinc accumulation when exposure levels increased, even when
exposure concentrations reached those that would be predicted to cause
chronic effects. This suggests that adverse effects related to Zn
exposure are independent of whole body accumulation. Due to the general
lack of increased whole body and tissue concentrations at higher
exposure levels, the zinc BCF data showed an inverse relationship to
exposure concentrations. In all cases, the relationship of BCF to
exposure was significant and negative. The slopes of the BCF/BAF –
exposure relations were: algae: -1.0, insects: -0.79, arthropods: -0.73,
molluscs: -0.83, salmonids: -0.92, Centrarchids: -0.80, Killifish:
-0.84, other fish: -0.87. Overall, species mean slope was -0.85 +/- 0.03
(McGeer et al 2003).
The physiological basis for the inverse relationship of BCF to zinc
exposure concentration arises from Zn uptake and control mechanisms. At
low environmental zinc levels, organisms are able to sequester and
retain Zn in tissues for essential functions. When Zn exposure is more
elevated, aquatic organisms are able to control uptake. There is clear
evidence that many species actively regulate their body Zn
concentrations, including crustaceae, oligochaetes, mussels, gastropods,
fish, amphipods, chironomids by different mechanisms (McGeer et al 2003).
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