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EC number: 809-911-5
CAS number: 1431329-07-5
Skin reactions / Irritation:
No irritation of the ears was observed in any of the animals examined.
White test substance remnants were present on the dorsal surface of the
ears of all animals at 25% (Days 2 and 3) and 50% (Days 1-3), which did
not hamper scoring of the skin reactions.
No mortality occurred and no clinical signs of systemic toxicity were
observed in the animals of the main study. Body weights and body weight
gain of experimental animals remained in the same range as controls over
the study period.
Macroscopy of the auricular lymph nodes and surrounding area:
All auricular lymph nodes of the animals of the experimental and control
groups were considered normal in size. No macroscopic abnormalities of
the surrounding area were noted for any of the animals.
One study is available which was conducted according to OECD Guideline
429 under GLP (Latour, 2014).
Since there was no indication that the test substance elicited a SI ≥ 3
when tested up to 50%, the test substance was not considered to be a
Animal test gave negative result (LLNA result SI < 3 (actual value 1.3)).
Therefore in accordance with Regulation (EC) No. 1272/2008 (as amended
by Regulation (EC) No. 286/2011) Table 3.4.2, this substance should not
be classified as skin sensitiser based on the test data.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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