Registration Dossier
Registration Dossier
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EC number: 203-972-6 | CAS number: 112-44-7
Endpoint summary
Administrative data
Description of key information
For details on key information, please see the respective endpoint summaries.
For a short summary of available information, please see below.
Additional information
Short-term toxicity to fish
Undecanal is acutely toxic for fish:
Acute fish toxicity was estimated using OECD QSAR Toolbox V.4.2 and following the standardized workflow (SW):
LC50 (trend analysis; 96 h; Actinopterygii) = 1.97 mg/L (95% CI: 0.274 mg/L to 14.2 mg/L).
Short-term toxicity to aquatic invertebrates
OECD TG 202 (GLP), acute immobilisation test on Daphnia magna with n-Undecanal:
the 48 hours-EC50 for Daphnia magna was 1459 μg/L (95% confidence limits: 1213 – 1643 μg/L) based on the summed up time-weighted mean measured concentrations of the test item n-undecanal and the reaction product, n-undecanoic acid.
Toxicity to aquatic algae
OECD TG 201 (GLP), Growth Inhibition Test with Pseudokirchneriella subcapitata with n-Undecanal:
Based on the summed up time-weighted mean measured concentrations of the test item n-undecanal and the reaction product, n-undecanoic acid the following (no)effect concentrations were derived:
EC50 (72 h; growth rate) = 132 µg/L (95% CI: 119 – 149 μg/L);
EC50 (72 h; yield) = 78.5 µg/L (95% CI: 25.7 – 245 μg/L);
NOEC (72 h; growth rate and yield) = 23.5 μg/L;
EC10 (72 h; growth rate) = 49.1 µg/L (95% CI: 38.5 – 60.0 µg/L)
Toxicity to microorganisms
In a reliable and valid Activated Sludge, Respiration Inhibition Test (Carbon and Ammonium Oxidation) performed compliant with GLP according to OECD 209 (2010), the test item n-undecanal was observed to moderately stimulate heterotrophic respiration up to a concentration of 41 mg/L (21% stimulation), but to inhibit nitrification (23% inhibition at 41 mg/L), resulting in a NOEC for total respiration of 41 mg/L.
Overall, the following (no)effect concentrations for inhibition of respiration were determined for the test item after an exposure period of 3 hours:
NOEC (3h) [mg/L]
total respiration: 41
heterotrophic respiration: 41
nitrification: 8.4
EC10 (3h) [mg/L]
total respiration: 51.1 (95% CI: 44.9 – 58.7)
heterotrophic respiration: 93.1 (95% CI: 75.2 – 121)
nitrification: 24.7 (95% CI: 19.9 – 30.2)
EC50 (3h) [mg/L]
total respiration: 128 (95% CI: 117 – 140)
heterotrophic respiration: 193 (95% CI: 148 – 233)
nitrification: 85.3 (95% CI: 74.3 – 99.2)
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