Registration Dossier
Registration Dossier
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EC number: 800-149-9 | CAS number: 1410795-90-2
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
Description of key information
The read-across partner ethylene diformate is readily biodegradable in a OECD 301B test: 86% degradation (CO2 evolution) occurred after 28 d. Thus, it is concluded that the substance 1,2,3-propanetriol, mono- and diformates can be considered to be readily biodegradable.
Key value for chemical safety assessment
- Biodegradation in water:
- readily biodegradable
Additional information
One experimental study is available investigating the biodegradation of ethylene diformate (CAS 629-15-2; Roulstone, 2013). The study was performed according to OECD 301B under GLP conditions. An initial test was carried out in which the test item was not readily biodegradable. However as the test item is known to hydrolyse to formic acid and ethylene glycol, both of which are readily biodegradable, this result was considered to be anomalous. Therefore, a second test was carried out using the same conditions as the first which resulted in 42 % degradation after 2 days and 85 % degradation after 14 days, thereby satisfying the 10-day window criterion. At the end of the study after 28 d the substance reached a biodegradation of 86%. In conclusion, the test material can be considered to be readily biodegradable according to the OECD criteria.
The result for ethylene diformate is used for the assessment of the substance 1,2,3-propanetriol, mono- and diformates in a read-across approach (for details and justification please refer to the read-across report). Thus,1,2,3-propanetriol, mono- and diformates is considered to be readily biodegradable.
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