Registration Dossier
Registration Dossier
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EC number: 800-149-9 | CAS number: 1410795-90-2
Endpoint summary
Administrative data
Description of key information
Additional information
One experimental study according to OECD guideline 301B confirmed that ethylene diformate (CAS 629-15-2) is readily biodegradable according to the OECD criteria (85% biodegradation after 14 d). This study is used in a read-across approach in the assessment of 1,2,3-propanetriol, mono- and diformates (for details and justification please refer to the attached read-across report). Based on the results of the OECD 301B study, persistency in the environment is not expected since the substance will be rapidly and ultimately degraded in the environment including sewage treatment plants (Guidance on information requirements and chemical safety assessment, Chapter R.7b; ECHA, 2012).
The test substance is susceptible to hydrolysis. The hydrolytical half-life (DT50), resulting in the breakdown products glycerol and formic acid, was determined to be 28.6 h at pH 7 and 20 °C in a study following OECD test guideline 111.
Considering the high water solubility (> 1000 g/L) and the low potential for adsorption to organic soil and sediment particles (Koc = 10 L/kg, KOCWIN v2.00), the target compartment for environmental distribution is expected to be surface water. However, persistency in this compartment can be excluded in view of the potential of the substance to undergo rapid hydrolysis, and its ready biodegradability. The vapour pressure reported for 1,2,3-propanetriol, mono- and diformates, 0.0985 Pa at 20 °C, indicates relatively low potential of the substance for volatilization. Thus, considerable evaporation from the water phase into air is not expected based on the low Henry’s Law constant (<< 1 Pa m³/mole; calculated from water solubility and vapour pressure).Therefore, significant distribution to air and subsequent transport to other environmental compartments is not anticipated. Furthermore, 1,2,3-propanetriol, mono- and diformates is not listed in Annex I of Regulation (EC) 2037/2000 on substances that deplete the ozone layer and does not belong to the greenhouse gases listed in the Intergovernmental Panel on Climate Change (IPCC) IPCC/TEAP Special Report, 2005. This substance is thus of no concern for the air compartment.
The potential for bioaccumulation of 1,2,3-propanetriol, mono- and diformates is considered to be negligible based on the low log Kow of < -1.7.
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