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EC number: 268-692-9
CAS number: 68133-60-8
Slight conjunctival redness (grade 1) was noted in two out of
three animals 1 hour after application and persisted until hour 48 in
these animals. The third animal showed obvious conjunctival redness
(grade 2) 1 hour after application, which decreased to slight
conjunctival redness at hour 24 and 48.
Slight conjunctival chemosis (grade 1) was noted in one out of
three animals 24 hours after application only.
Slight discharge (grade 1) was noted in all animals 1 hour after
application and persisted in one animal up to 24 hours after application.
Additional findings like injected scleral vessels in a
circumscribed area were noted in all animals at hour 1 after application
and persisted in one animal each until 24 or 48, respectively.
The ocular reactions were reversible in all animals within 72
hours after application.
Mean scores calculated for each animal over 24, 48 and 72 hours
were 0.0, 0.0 and 0.0 for corneal opacity, 0.0, 0.0 and 0.0 for iris
lesions, 0.7, 0.7 and 0.7 for redness of the conjunctiva and 0.3, 0.0
and 0.0 for chemosis.
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