Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Physical & Chemical properties

Water solubility

Currently viewing:

Administrative data

Link to relevant study record(s)

Reference
Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
OECD Guideline 105 (Water Solubility)
Deviations:
no
Qualifier:
according to guideline
Guideline:
EU Method A.6 (Water Solubility)
Deviations:
no
GLP compliance:
yes
Type of method:
flask method
Specific details on test material used for the study:
DE 535 (Ester) pure
Lot# TSN100400
Purity: 99.7%
Key result
Water solubility:
9.08 mg/L
Conc. based on:
test mat.
Temp.:
20 °C
Remarks on result:
other: Purified water
Key result
Water solubility:
6.93 mg/L
Conc. based on:
test mat.
Temp.:
20 °C
pH:
5
Key result
Water solubility:
7.86 mg/L
Conc. based on:
test mat.
Temp.:
20 °C
pH:
7
Details on results:
Water solubility at 20°C
Purified water: 9.08±0.47 mg/L (C. of V. =5.2%)
pH 5 buffer: 6.93±1.04 mg/L (C. of V. =15.0%)
pH 7 buffer: 7.86±1.04 mg/L (C. of V. =13.2%)
Conclusions:
Water solubility at 20°C
Purified water: 9.08 mg/L
pH 5 buffer: 6.93 mg/L
pH 7 buffer: 7.86 mg/L
Executive summary:

The study was conducted to determine the water solubility of the test substance according to regulatory guidelines: OECD 105 and EEC Method A.6.

Water solubility at 20°C

Purified water: 9.08±0.47 mg/L (C. of V. =5.2%)

pH 5 buffer: 6.93±1.04 mg/L (C. of V. =15.0%)

pH 7 buffer: 7.86±1.04 mg/L (C. of V. =13.2%)

Tests for the solubility of the test substance in pH 9 buffer solution were not considered relevant due to known rapid hydrolysis of the test material at this pH.

Description of key information

OECD 105; EU Method A.6

Key value for chemical safety assessment

Water solubility:
9.08 mg/L
at the temperature of:
20 °C

Additional information

Purified water: 9.08mg/L at 20°C

pH5: 6.93 mg/L at 20oC

pH 7: 7.86 mg/L at 20oC