Registration Dossier
Registration Dossier
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EC number: 915-389-0 | CAS number: -
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
TetraEGME: Daphnia magna 48hr (TetraEGME) EC50 :22.9g/l. QSAR prediction: 4hr EC50 154g/L
PentaEGME: Daphnia magna QSAR prediction: 4hr EC50 321g/L
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 22.9 g/L
Additional information
Measured data is available for the acute toxicity in daphnia magna of the most toxic component of this multi-contituent substance. A study with the substance tetraethylene glycol methyl ether (TetraEGME) established that the EC50 was around 22.9g/l. A QSAR seems to under predict the toxicity of this molecule at around 154g/l but predicts that the other major component would have a lower toxicity of 321g/l and that therefore, as with fish and algal toxicity, it decreases with increasing molecular weight. On this basis, it seems reasonable to conclude that the acute toxicity EC50 of the substance will be no more toxic than TetraEGME that selecting the measured EC50 for this substance is a conservative choice for the key parameter.
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