Registration Dossier
Registration Dossier
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EC number: 907-242-4 | CAS number: -
Endpoint summary
Administrative data
Key value for chemical safety assessment
Toxicity to reproduction: other studies
Description of key information
The only data for the assessment of the reproductive toxicity of lauryl chloride are publicly available, but proprietary data, which have been submitted to the US EPA under the Toxic Substances Control Act (TSCA). In a combined oral repeated-dose/reproductive screening study in rats (according to OECD 422 and US EPA TSCA 799.9365), the NOAEL for reproduction was at the highest dose tested of 1000 mg/kg, whereas the NOAEL for development was at 300mg/kg based on lower postnatal survival and reduced pup body weights in the high dose group of 1000 mg/kg.
Justification for classification or non-classification
Information on reproductive toxicity of lauryl chloride was obtained in a combined oral repeated-dose/reproductive screening study in rats. In this study, the NOAEL for reproduction was at the highest dose tested of 1000 mg/kg, whereas the NOAEL for development was at 300 mg/kg. Based on the results of this study there are no hints for reproductive toxicity of lauryl chloride that would lead to a classification according to Regulation (EC) 1272/2008.
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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