Registration Dossier
Registration Dossier
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EC number: 221-043-3 | CAS number: 2983-37-1
Partition coefficient
Administrative data
Link to relevant study record(s)
- Endpoint:
- partition coefficient
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- From 23-05-2016 to 21-10-2016
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Remarks:
- OECD guideline study, conducted under GLP. Test substance adequately identified. Therefore full validation applies.
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 107 (Partition Coefficient (n-octanol / water), Shake Flask Method)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.8 (Partition Coefficient)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EPA OPPTS 830.7550 (Partition Coefficient, n-octanol / H2O, Shake Flask Method)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- flask method
- Partition coefficient type:
- octanol-water
- Analytical method:
- gas chromatography
- Key result
- Type:
- log Pow
- Partition coefficient:
- 3.9
- Temp.:
- 20 °C
- pH:
- 7.6
- Conclusions:
- The substance has not potential to bioaccumulate in the environment, according to CLP classification criteria for aquatic chronic toxicity (log Pow <4).
- Executive summary:
The partition coefficient of the test substance was measured according to the OECD 107/EU A8 guideline, gas chromatography method.
Partition coefficient (log Pow) = 3.9 (pH 7.6, 20°C)
Reference
Description of key information
The data is relevant for classification in aquatic chronic toxicity hazard class, according to CLP criteria.
The substance has no potential for bioaccumulation (log Kow<4).
Key value for chemical safety assessment
- Log Kow (Log Pow):
- 3.9
- at the temperature of:
- 35 °C
Additional information
A fully reliable experimental study, conducted according to OECD guideline, HPLC method, is available. It is considered as a key study. The result is retained as key data.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
