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EC number: 218-620-7
CAS number: 2206-94-2
The test item α-methylenebenzyl acetate
was administered to 5 females at the limit dose of 2000 mg/kg. There
was no test item related mortality, but signs of toxicity such as
lacrimation, reduced activity, lethargy and mild spasm in hind legs were
observed in the Sighting Study during the first 24 hours. Therefore, the
animal was observed for a further 24 hours. After this time, all
observed signs were no longer recorded. The Main Test started with the
dose of 2000 mg/kg. Four additional animals were dosed in the Main Study
with the dose of 2000 mg/kg. One female died 24 hours after dosing. In
other animals, the same clinical
signs were observed. Within 48 hours, all signs were no longer observed.
No body weight losses were observed between one and two week after
administration of the test item. Neither visible change of health nor
negative reactions were registered during the 14- day observation
period. No macroscopic changes were noticed.
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