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EC number: 939-478-9
CAS number: -
In an oral OECD 421 screening study rats were given 0, 100, 500 or 1000
mg/kg bw/d of URALAC P 1910C/URALAC P 1920C formulated in propylene
glycol for 7 days/week for 28 days (males) and 41 -45 days (females). No
adverse effects were observed on mortality, clinical signs, body weight(
gain) and food consumption, macroscopy and histopathology. Reproduction
parameters consisting of mating, fertility and conception indices,
precoital time, number of corpora lutea and implantation sites,
gestation index and duration, parturition and maternal care showed no
effects. Sex ratio and early postnatal pup development (mortality,
clinical signs, body weight and macroscopy) were not affected.
Based on the absence of adverse effects, the NOAEL for maternal and
developmental toxicity was determined to be at least 1000 mg/kg bw/day.
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