Registration Dossier
Registration Dossier
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EC number: 205-524-5 | CAS number: 142-16-5
Endpoint summary
Administrative data
Description of key information
A case report of a 62-year old woman with a history of severe dermatitis. A patch testing was conducted according to the British Contact Dermatitis Society standard series but insufficient detail on the experimental procedure and results are available for assessment.
Additional information
A case report presented a 62-year old woman with a history of severe intermittent facial dermatitis including itchy, burning sensation and oedema was reported. Further patch testing was conducted to individual ingredients of the moisturizing lotion (2, 5, and 10% of dioctyl maleate in petrolatum). Results showed a positive reaction to dioctyl maleate at all concentrations. Control patients were negative. Authors suggested that dioctyl maleate was a skin sensitizer.
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