Registration Dossier
Registration Dossier
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EC number: 234-456-9 | CAS number: 12004-39-6
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
A key study is provided for the assessment of short-term toxicity to fish. The study was conducted in accordance with GLP and OECD test guidelines with no deviations.
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 0.36 mg/L
Additional information
Key study:
The acute toxicity of dialuminium titanium pentaoxide to fish was determined in a study which was carried out in accordance with OECD guideline 203 ''Fish, Acute Toxicity Test''. As the test substance is a poorly soluble inorganic compound, medaka (Oryzias latipes) were exposed to test solution prepared at its maximum achievable saturation level. Concentrations of aluminium and titanium were determined by ICP-MS which were then used to calculate equivalent concentrations of the test substance. The loading rate used in the test was 100 mg/L.
After 96 hours of exposure no mortality or abnormal effects were observed. The 96hr LC50was determined to be >0.468 mg/L based on aluminium analysis and >0.360 mg/L based on titanium analysis. All validity criteria were met and this study is considered reliable without restriction.
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