Reaction mass of Benzenamine, N,N-dimethyl- , molybdate, tungstate & phosphates

Short-term toxicity to fish

Link to relevant study record(s)

Reference

Endpoint:

short-term toxicity to fish

Type of information:

read-across from supporting substance (structural analogue or surrogate)

Adequacy of study:

weight of evidence

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

data from handbook or collection of data

Remarks:

Experimental data of read across chemicals

Justification for type of information:

Data for the target chemical is summarized based on the structurally similar read across chemicals

Reason / purpose for cross-reference:

read-across source

Reason / purpose for cross-reference:

read-across source

Qualifier:

according to guideline

Guideline:

other: As mention in below principle

Principles of method if other than guideline:

WoE report is based on two short term toxicity study of fish for the test chemical :1 and 2

GLP compliance:

not specified

Specific details on test material used for the study:

- Name of test material : Reaction mass of Benzenamine, N,N-dimethyl- , molybdate, tungstate & phosphates - Substance type: Organic- Physical state: Solid- Physical Appearance: Violet powder

Analytical monitoring:

not specified

Vehicle:

not specified

Test organisms (species):

other: fish

Test type:

static

Water media type:

freshwater

Total exposure duration:

96 h

Reference substance (positive control):

not specified

Key result

Duration:

96 h

Dose descriptor:

LC50

Effect conc.:

0.6 mg/L

Nominal / measured:

nominal

Conc. based on:

test mat.

Basis for effect:

mortality (fish)

Remarks on result:

other: In 1st study

Duration:

96 h

Dose descriptor:

LC50

Effect conc.:

0.91 mg/L

Nominal / measured:

nominal

Conc. based on:

test mat.

Basis for effect:

mortality (fish)

Remarks on result:

other: In 2nd study

Validity criteria fulfilled:

not specified

Conclusions:

1. After the exposure of test chemical with fishes lethal effect at which 50% mortality were observed and measured. The LC50 was determine to be 0.60 mg/l.2. Based on the mortality of fish by the test chemical for 96 hrs, the LC50 was determine to be 0.91 mg/l.Based on above experimental studies it was concluded that the reaction mass of Benzenamine, N,N-dimethyl-molybdate, tungstate & phosphates was toxic and classified as aquatic acute 1 as per the CLP classification criteria.

Executive summary:

Summarized result for data available for the structurally and functional similar read across chemicals study has been reviewed to determine the toxicity of the test reaction mass of Benzenamine, N,N-dimethyl- , molybdate, tungstate & phosphates on the growth of fish. The studies are as mentioned below:

 

In study one short term toxicity study was carried out to determine the nature of test chemical when exposed with the fishes by providing time 96 hrs.After the exposure of test chemical with fishes lethal effect at which 50% mortality were observed and measured. The LC50 was determine to be 0.60 mg/l. Based on the LC50, chemical was consider as toxic and classified as aquatic acute 1 as per the CLP classification criteria.

First study was supported by second. Aim of this study was to determine the short term toxicity of test chemical on mortality of fish. Test was carried out according to the OECD Guideline 203 (Fish, Acute Toxicity Test) 2-benzylideneheptanal under the static system. Based on the mortality of fish by the test chemical for 96 hrs, the lethal concentration LC50 was determine to be 0.91 mg/l. It can be concluded from the LC50 value that the test chemical was toxic to the fish and thus can be considered to be classified in "aquatic acute category 1" as per the CLP classification criteria.

Based on above experimental studies it was concluded that the reaction mass of Benzenamine, N,N-dimethyl- , molybdate, tungstate & phosphates was toxic and classified as aquatic acute 1 as per the CLP classification criteria.

Description of key information

1. After the exposure of test chemical with fishes lethal effect at which 50% mortality were observed and measured. The LC50 was determine to be 0.6 mg/l.

2. Based on the mortality of fish by the test chemical for 96 hrs, the LC50 was determine to be 0.91 mg/l.

Based on above experimental studies it was concluded that the reaction mass of Benzenamine, N,N-dimethyl-molybdate, tungstate & phosphates was toxic and classified as aquatic acute 1 as per the CLP classification criteria.

Key value for chemical safety assessment

Fresh water fish

Fresh water fish

Effect concentration:

0.6 mg/L

Additional information

Summarized result for data available for the structurally and functional similar read across chemicals study has been reviewed to determine the toxicity of the test reaction mass of Benzenamine, N,N-dimethyl- , molybdate, tungstate & phosphates on the growth of fish. The studies are as mentioned below:

 

In study one short term toxicity study was carried out to determine the nature of test chemical when exposed with the fishes by providing time 96 hrs.After the exposure of test chemical with fishes lethal effect at which 50% mortality were observed and measured. The LC50 was determine to be 0.6 mg/l. Based on the LC50, chemical was consider as toxic and classified as aquatic acute 1 as per the CLP classification criteria.

First study was supported by second. Aim of this study was to determine the short term toxicity of test chemical on mortality of fish. Test was carried out according to the OECD Guideline 203 (Fish, Acute Toxicity Test) 2-benzylideneheptanal under the static system. Based on the mortality of fish by the test chemical for 96 hrs, the lethal concentration LC50 was determine to be 0.91 mg/l. It can be concluded from the LC50 value that the test chemical was toxic to the fish and thus can be considered to be classified in "aquatic acute category 1" as per the CLP classification criteria.

Based on above experimental studies it was concluded that the reaction mass of Benzenamine, N,N-dimethyl- , molybdate, tungstate & phosphates was toxic and classified as aquatic acute 1 as per the CLP classification criteria.