4-methyl-4-phenylpentan-2-ol

Ecotoxicological Summary

Hazard for aquatic organisms

Freshwater

Hazard assessment conclusion:

PNEC aqua (freshwater)

PNEC value:

0.036 mg/L

Assessment factor:

1 000

Extrapolation method:

assessment factor

PNEC freshwater (intermittent releases):

0.361 mg/L

Marine water

Hazard assessment conclusion:

PNEC aqua (marine water)

PNEC value:

0.004 mg/L

Assessment factor:

10 000

Extrapolation method:

assessment factor

STP

Hazard assessment conclusion:

PNEC STP

PNEC value:

1.8 mg/L

Assessment factor:

10

Extrapolation method:

assessment factor

Sediment (freshwater)

Hazard assessment conclusion:

PNEC sediment (freshwater)

PNEC value:

0.558 mg/kg sediment dw

Extrapolation method:

equilibrium partitioning method

Sediment (marine water)

Hazard assessment conclusion:

PNEC sediment (marine water)

PNEC value:

0.056 mg/kg sediment dw

Extrapolation method:

equilibrium partitioning method

Hazard for air

Air

Hazard assessment conclusion:

no hazard identified

Hazard for terrestrial organisms

Soil

Hazard assessment conclusion:

PNEC soil

PNEC value:

0.09 mg/kg soil dw

Extrapolation method:

equilibrium partitioning method

Hazard for predators

Secondary poisoning

Hazard assessment conclusion:

no potential for bioaccumulation

Additional information

PNECs were derived based on test data following standard guidelines. All data are considered to be reliable and relevant for the endpoint concerned.

 

Short-term aquatic data in freshwater are available for three trophic levels for the test item. The most sensitive endpoint was determined to be fish, with a LC50 of 36.12 mg/L (Hairong 2016). This endpoint was used to derive the PNECs for freshwater, marine water and intermittent releases by assessment factor method, and freshwater sediment, marine sediment and soil by equilibrium partitioning approach.

 

For derivation of the PNEC for STP, the NOEC of 18 mg/L was taken from the toxicity control of a ready biodegradability test. A PNEC of 1.8 mg/L is derived by applying an assessment factor of 10.

 

The test item has low vapour pressure (7.4, 10.6 and 54.3 Pa at 20, 25 and 50°C, respectively (Smeykal 2015), therefore it is not a precursor to ozone formation and is not expected to be a significant contribution to global warming. The test item is not an ozone depleting substance as defined by the Montreal Protocol and does not contain chemical constituents that would lead to acidification.

 

No hazard is expected from secondary poisoning. The measured log Kow value of 2.82 indicates that the test item is not potentially bioaccumulative. Since the test item has no bioaccumulation potential, a secondary poisoning assessment is not required.

Conclusion on classification

Acute aquatic data are available for three trophic levels for the test item. The most sensitive endpoint was determined to be fish, with a 96-hour LC50 of 36 mg/L (Noack 2016). The 48-hour EC50 for immobilisation of Daphnia was determined to be 39.8 mg/L (Noack 2015). The 72-hour EC50 for growth rate of algae, P. subcapitata was determined to be 57.6 mg/L (Scheerbaum 2015).

Chronic aquatic data are available only for algae (72-h EC10 = 14.7 mg/L, Scheerbaum 2015). The test item achieved biodegradation of 47 % after 28 days and therefore is considered to be not readily biodegradable (Maischak 2015).

As the EC10 value determined in the algae study is > 1 mg/L and the substance is not readily biodegradable, based on chronic data the test item is not classified as hazardous to the aquatic environment. However, the effect values determined in the short-term aquatic studies are > 10 to ≤ 100 mg/L, and the substance is not readily biodegradable, therefore, by applying the most protective classification, the test item is classified as hazardous to the aquatic environment with a Chronic Category 3 classification.