Propanamide, N-[4-(2,4-dihydroxyphenyl)-2-thiazolyl]-2-methyl-

Density

Administrative data

Endpoint:

relative density

Type of information:

experimental study

Adequacy of study:

key study

Study period:

9 - 22 Jan 2014

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

2014

Report date:

2014

Materials and methods

Test guideline

Test guideline 1

Qualifier:

according to guideline

Guideline:

OECD Guideline 109 (Density of Liquids and Solids)

Deviations:

no

Test guideline 2

Qualifier:

according to guideline

Guideline:

EU Method A.3 (Relative Density)

Deviations:

no

GLP compliance:

yes (incl. QA statement)

Remarks:

Landesamt für Umwelt, Wasserwirtschaft und Gewerbeaufsicht, Mainz, Germany

Type of method:

pycnometer method

Test material

Test material information

Constituent 1

Reference substance name:

N-[4-(2,4-dihydroxyphenyl)-1,3-thiazol-2-yl]-2-methylpropanamide

EC Number:

807-621-3

Cas Number:

1428450-95-6

Molecular formula:

C13H14N2O3S

IUPAC Name:

N-[4-(2,4-dihydroxyphenyl)-1,3-thiazol-2-yl]-2-methylpropanamide

Test material form:

solid: particulate/powder

Results and discussion

Density

Density 1

Type:

density

Density:

1.404 g/cm³

Temp.:

20 °C

Density 2

Key result

Type:

relative density

Density:

1.404

Temp.:

20 °C

Any other information on results incl. tables

Measured values:

First Determination				Error rel.	Error abs.
Temperature	19.8	°C			0.1
Density of water	0.998203	g/cm^3		2.00%	0.0002
Weighing #	m1	m2	m3	m4	m5
Item	Pycn. empty	Pycn.+ H2O	Pycn. + repl.liq.	Pycn. + test item	Pycn. + test item + repl. liq.
Mass in g	42.6064	92.8955	81.3322	46.8867	83.2625
Temperature in °C	19.8	19.8	20.0	19.8	20.2
Volume of Pycnometer	50.3796	cm^3
Density of Replacement Liquid	0.7687
Density of Test Item	1.4001	g/cm^3		0.0678%	0.0009
Second Determination				Error rel.	Error abs.
Temperature	20.0	°C	20		0.1
Density of water	0.998203	g/cm^3		2.00%	0.0002
Weighing #	m1	m2	m3	m4	m5
Item	Pycn. empty	Pycn.+ H2O	Pycn. + repl.liq.	Pycn. + test item	Pycn. + test item + repl. liq.
Mass in g	42.6061	92.8919	81.3310	47.2981	83.4624
Temperature in °C	20.2	20.0	20.2	20.2	20.0
Volume of Pycnometer	50.3763	cm^3
Density of Replacement Liquid	0.7687
Density of Test Item	1.4086	g/cm^3		0.0624%	0.0009

Presentation of Results

Results of the single determinations with the respective error as well as the mean value and its standard deviation are presented in the following tables:

Results of Single Determinations

Determination	Density in g/cm^3	Error of Determ. in g/cm^3
1	1.4001	0.0009
2	1.4086	0.0009

 

Results – Mean Values

Parameter	Value	Unit	Standard Deviation	Relative Standard Deviation
Volume of Pycnometer	50.38	cm^3	0.0023	0.00 %
Density of Test Item	1.4043	g/cm^3	0.0060	0.00 %
Density of Test Item	1404.3	kg/m^3	6.0
Relative Density of Test Item	1.4043		0.0060

The density of the test itemN-[4-(2,4-dihydroxyphenyl)thiazol-2-yl]isobutyramidewas calculated as 1.4043 ± 0.0009 g/cm³at 20.0 ± 0.2 °C which is the mean of two values. Precision of the value is given as maximal error of a single determination.

Correspondence of the values is good. Therefore, the study is considered valid.

Applicant's summary and conclusion

Conclusions:

NDHPTMPA has a relative density of 1.4043 at 20°C

Executive summary:

NDHPTMPA has a relative density of 1.4043 at 20°C