Registration Dossier
Registration Dossier
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EC number: 203-401-0 | CAS number: 106-47-8
Eye irritation
Administrative data
- Endpoint:
- eye irritation: in vivo
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- other:
- Rationale for reliability incl. deficiencies:
- other: Data from handbook of collection of data.
Data source
Reference
- Reference Type:
- publication
- Title:
- No information
- Year:
- 2 003
- Bibliographic source:
- International Programme on Chemical Safety's Concise International Chemical Assessment Documents. Number 48: 4-Chloroaniline (2003). Available from, as of February 22, 2005: http://www.inchem.org/pages/cicads.html
Materials and methods
- Principles of method if other than guideline:
- No guideline known, only database endpoints.
- GLP compliance:
- not specified
Test material
- Reference substance name:
- 4-chloroaniline
- EC Number:
- 203-401-0
- EC Name:
- 4-chloroaniline
- Cas Number:
- 106-47-8
- Molecular formula:
- C6H6ClN
- IUPAC Name:
- 4-chloroaniline
Constituent 1
Test animals / tissue source
- Species:
- rabbit
- Strain:
- not specified
Test system
- Vehicle:
- not specified
- Controls:
- not specified
Results and discussion
In vivo
- Irritant / corrosive response data:
- Slightly irritating to rabbit eyes (grade 1-2 effects).
Applicant's summary and conclusion
- Interpretation of results:
- slightly irritating
- Remarks:
- Migrated information Criteria used for interpretation of results: EU
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