Registration Dossier
Registration Dossier
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EC number: 206-119-6 | CAS number: 302-23-8
Endpoint summary
Administrative data
Description of key information
Oral (Rat-Wistar, GLP, non-audited report, OECD TG423): LD50 > 2000 mg/kg
[Schering AG, Report No. X053; 1995-11-27]
Dermal (Rat-Wistar, GLP, non-audited report, OECD TG402 & 404): LD50 > 2000 mg/kg
[Schering AG, Report No. X058; 1996-01-09]
Key value for chemical safety assessment
Additional information
The single oral administration of ZK 5189 to male and female Wistar rats was tolerated without any treatment-related clinical or macroscopic pathological findings. Acute oral toxicity of ZK 5189 in Wistar rats is above 2000 mg/kg body weight. [Schering AG, Report No. X053; 1995-11-27]
The single dermal administration of ZK 5189 to male and female Wistar rats was well tolerated without any treatment-related clinical or macroscopic pathological findings. Acute dermal toxicity of ZK 5189 is above 2000 mg/kg body weight. [Schering AG, Report No. X058; 1996-01-09]
Justification for classification or non-classification
Since LD50 > 2000 mg/kg there is no classification required according to Directive 67/548/EEC and Regulation (EC) 1272/2008 (CLP).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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