Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
toxicity to microorganisms
Type of information:
experimental study
Adequacy of study:
other information
Reliability:
1 (reliable without restriction)

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1995
Report date:
1995

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
DIN 38412-8 (Pseudomonas Zellvermehrungshemmtest)
GLP compliance:
yes (incl. QA statement)

Test material

Constituent 1
Chemical structure
Reference substance name:
Hydroxyprogesterone acetate
EC Number:
206-119-6
EC Name:
Hydroxyprogesterone acetate
Cas Number:
302-23-8
Molecular formula:
C23H32O4
IUPAC Name:
(1R,3aS,3bR,9aR,9bS,11aS)-1-acetyl-9a,11a-dimethyl-7-oxo-1H,2H,3H,3aH,3bH,4H,5H,7H,8H,9H,9aH,9bH,10H,11H,11aH-cyclopenta[a]phenanthren-1-yl acetate

Study design

Total exposure duration:
16 h

Results and discussion

Applicant's summary and conclusion

Executive summary:

The toxicity of the test substance was also tested on bacterial microroganisms (Pseudomonas putida) according to the method DIN 38412, L8. The microorganisms were incubated with the test substance over a period of 16 hours. The EC10 for population growth was higher than a saturated solution (Schering AG, X016, 27 Jul 1995).

The study was conducted under GLP.