Registration Dossier
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EC number: 206-119-6 | CAS number: 302-23-8
Vapour pressure
Administrative data
Link to relevant study record(s)
Description of key information
Valid experimental study according to EU method A.4. (Effusion method: Vapor pressure balnce).
General Physical Chemistry, Schering AG, Berlin, Study report LY83 (APC 128/96), dated 1996-11-14.
Key value for chemical safety assessment
Additional information
The temperature dependence of the vapour pressure was determined with the Knudsen effusion method using a vapour pressure balance in the temperature range 130 ‑ 165°C.
The following vapour pressures were calculated for 20, 25 and 30 °C using a semilogarithmic linear regression based on the Antoin equation to be (with 95 %confidence intervall):
P20 = 6.4 · 10-12 Pa (5.0 · 10-13 - 8.1 · 10-11 Pa)
P25 = 2.0 · 10-11 Pa (1.9 · 10-12 - 2.3 · 10-10 Pa)
P30 = 6.3 · 10-11 Pa (6.5 · 10-12 - 6.0 · 10-10 Pa)
The Henry constant H (at 25°C) was calculated to be H = 9.7 · 10 -13 at 25°C.
Thus hydroxyprogesterone acetate is to be considered nonvolatile in aqueous solution.
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