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Environmental fate & pathways

Biodegradation in soil

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A constituent approach has been used to assess the degradation potential of the substance. Many of the substance constituents are readily biodegradable based on predictions made using the BIOWIN model (US EPA 2010). For hydrocarbon constituents, half life values have been predicted using the BIOHCWIN model (US EPA 2010). For diisopropylether and 1-isopropoxypropane biodegradation simulation studies are not required as the substances do not have a high potential for adsorption to sediment and are highly volatile.

Key value for chemical safety assessment

Additional information

The constituents 1-propanol, propene, 2-propanone, 2-propanol and C6 alcohols are predicted to be readily biodegradable based on BIOWIN predictions (US EPA 2010). Most C6 alkane and alkene constituents are predicted to be readily biodegradable, with the exception of 2,3-dimethylbutane and 2,3-dimethyl-2-butene. Some C9 alkanes and alkenes are also predicted to be readily biodegradable (nonene, nonane and 2-methyl-1-octene).


Predictions were determined for each representative constituent for which the model was suitable, using the BIOHCWIN model. Persistence potential was determined based on half-life (Persistent if: half-life >40 days). All of the constituents for which the model was suitable were found to be not persistent except for cyclohexane (half-life: 55.38).


For diisopropylether and 1-isopropoxypropane, biodegradation simulation studies are not required as the substances do not have a high potential for adsorption to sediment and are highly volatile. This is supported by the n-octanol/water partition coefficient information indicating that diisopropylether has a log Kow of 1.52 – 1.88 and 1-isopropoxypropane has a log Kow of 1.96 (predictions and experimental values from KOWWIN v1.68). Vapour pressure values of 19900 Pa (diisopropylether, experimental) and 11400 Pa (1-isopropoxypropane, predicted) and Henry’s law constant values of 250 Pa/m3/mol (diisopropylether, experimental) and 271 Pa/m3/mol (1-isopropoxypropane, predicted), taken from MPBPVP v1.43 and HENRYWIN v3.20, also support this conclusion.

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