Registration Dossier
Registration Dossier
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EC number: 441-420-8 | CAS number: 113889-23-9
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
Description of key information
The Ready Biodegradability of Cyclobutanate was determined by the CO2 Evolution Test according to OECD TG 301B under GLP. The concentration tested was 10 mg C/l, with an activated sludge concentration of 30 mg suspended solids/l. The validity of the test was confirmed with control solutions with inoculum and the standard material, sodium benzoate and a toxicity control which attained 73% degradation after 28 days. This confirming that the test material was not toxic to the sewage treatment micro-organisms used in the study. The total biodegradation percentage after 28 days is 43%, including the inorganic carbon present in the solution on day 28 and the carry-over in the second absorber. Cyclobutanate is not readily biodegradable under the test conditions of OECD Guideline No 301B.
Key value for chemical safety assessment
- Biodegradation in water:
- not biodegradable
- Type of water:
- freshwater
Additional information
In addition, a ready biodegradability test according to OECD TG 301C (2015, MITI test, based on oxygen consumption) was performed. The test item concentration was 100 mg/l and the activated sludge 30 mg/l, The substance showed 34% degradation after 28 days. Because the substance was not readily biodegradable the key metabolites were also determined, which was Cycla-alcohol (Cas no: 3385 -61-3). No Cyclobutanate or butanoic acid was found. Overall, after 28 days: 100% Cyclobutanate was degraded: 34% was degraded to CO2 (likely the butanoic acid chain) and 66% remained as Cycla-alcohol, completing the mass balance.
In another ready biodegradation study also according to OECD TG 301C (2002) 22% biodegradation was found and no Cyclobutanate; degradation products were seen but not identified.
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