Registration Dossier
Registration Dossier
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EC number: 203-756-1 | CAS number: 110-31-6
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
EC10 (3 h) > 1000 mg/L for microorganisms (OECD 209, full test)
Key value for chemical safety assessment
Additional information
There is no data available on the potential of toxicity to algae of Amides, C16 and C18-C20 (even numbered, unsaturated), N,N’-ethylenebis. In order to fulfil the standard information requirements set out in Annex VIII, 9.1.4, in accordance with Annex XI, 1.5, of Regulation (EC) No 1907/2006, read-across from a structurally related substance is conducted.
A detailed justification for the grouping of chemicals and read-across is provided in Sections 6.1 and 13.
The toxicity of Amides, C16 and C18-C20 (even numbered, unsaturated), N,N’-ethylenebis to microorganisms was assessed in a read across approach using data from the structural analogue Amides, C16-C18 (even), N,N'-ethylenebis. The toxicity of the test substance to activated sludge was investigated in one key study according to OECD 209 (Clariant, 1989). Mircoorganisms were exposed for 3 h to nominal concentrations of 100, 180, 320, 580 and 1000 mg/L. The results of this test show no effects on the respiration rate of activated sludge up to the highest nominal test concentration of 1000 mg/L. Therefore, the EC10 and EC50 (3 h) were determined to be > 1000 mg/L. Disturbances in the biodegradation process of activated sludge are not anticipated.
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