Registration Dossier
Registration Dossier
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EC number: 915-790-0 | CAS number: -
Long-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
For Daphnia magna, a 21-day LOEC and NOEC of 3.2 and 1.6 mg/L WAF, respectively, based on immobilization was determined.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 1.6 mg/L
Additional information
A reliable long-term toxicity study with invertebrates is available for reaction mass of Amines, coco alkyl and ß-Alanine, N-(2-carboxyethyl)-, N-coco alkyl derivs. and ß-Alanine, N-coco alkyl derivs. and included in the dossier.
Parr (2013) conducted a reliable (Klimisch 1) GLP compliant study following OECD 211 methods. Based on the results of a preliminary range-finding test, less than 24 hr old Daphnia magna were exposed (10 replicates of a single daphnid per group) to Water Accommodated Fractions (WAFs) of the test substance without solvent over a range of nominal loading rates of 0.20, 0.40, 0.80, 1.6 and 3.2 mg/L for a period of 21 days under semi-static test conditions. The numbers of live and dead adult Daphnia and young daphnids (live and dead) were determined daily. The Daphnia were fed daily with a mixture of algal suspension and Tetramin®flake food suspension. Study results indicate a 21-day LOEC and NOEC of 3.2 and 1.6 mg/L WAF, respectively, based on immobilization. Determination of NOEC based on reproduction was not possible due to test organism performance. Consequently, this study will be taken for the long-term toxicity of the test substance to invertebrates endpoint.
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