Registration Dossier
Registration Dossier
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EC number: 262-967-7 | CAS number: 61788-32-7
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
The LC50 (96h) was above 1000 mg/L test substance (nominal concentration) for several fish species. In all cases, the LC50 (96h) was above the water solubility of the substance. Since none of the studies was performed according to the most recent guidelines, a Weight of Evidence approach was used for the evaluation of short-term toxicity to fish.
Key value for chemical safety assessment
Additional information
Several tests evaluating the acute toxicity of hydrogenated terphenyls towards different fish species are available (Griffin, 1979; Thompson, 1979; John O’H. Rice, 1972; Adams 1979; BTL 1972 a&b),. None of them followed the standard guidelines for short-term toxicity testing to fish (e. g. OECD 203), although two tests were set up according to the EPA-660/3-75-009 -Methods for acute toxicity tests with fish, macroinvertebrates and amphibians. Apart from one, all studies were carried out with the primary test substance containing 40 % hydrogenated terphenyls, the substance in the one study containing 30 % hydrogenated terphenyls. Species tested were rainbow trout (O. mykiss), bluegill (L. macrochirus) and fathead minnow (P. promelas). As far as reported, two tests were limit tests, whereas one test employed a range of exposure concentrations. In all cases, nominal test concentrations were reported. In four out of five tests the LC50(96h) was reported to be > 1000 mg/L (one of these tests also reported a NOEC > 1000 mg/L). The result of the fifth test yielded a LC50(96h) > 10 - < 100 ppm. It should be noted that this fifth test was the only one that was not carried out with a test substance with only 30 % hydrogenated terphenyls.
A comparison of the results shows that, although the tests were (as far as known) conducted under static conditions and no data on measured test concentrations are available, hydrogenated terphenyl is not acutely toxic to fish at concentrations well above its water solubility.
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