Registration Dossier
Registration Dossier
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EC number: 202-448-4 | CAS number: 95-76-1
Toxicity to birds
Administrative data
- Endpoint:
- short-term toxicity to birds: acute oral toxicity test
- Type of information:
- experimental study
- Adequacy of study:
- other information
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: Information about test method are missing and only short-term investigation with birds determining the acute lethal effect after oral application is available. This study cannot be used for the assessment
Data source
Referenceopen allclose all
- Reference Type:
- publication
- Title:
- Arch. Environ. Contam. Toxicol. 12,|355-382
- Author:
- Schafer et al. (1983):
- Year:
- 1 983
- Reference Type:
- secondary source
- Title:
- 3,4-dichloroaniline (3,4-DCA)
- Author:
- EU-Risk Assessment Report
- Year:
- 2 006
- Bibliographic source:
- EUR 22235 EN; ISSN 1018-5593
- Reference Type:
- review article or handbook
- Title:
- 2,4-Dichloranilin; 2,5-Dichloranilin; 3,4-Dichloranilin
- Author:
- Beratergremium für umweltrelevante Altstoffe (BUA)
- Year:
- 1 994
- Bibliographic source:
- Wissenschaftliche Verlagsgesellschaft, BUA report 140
Materials and methods
Test guideline
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- Acute oral toxicology tests
- GLP compliance:
- no
Test material
- Reference substance name:
- 3,4-dichloroaniline
- EC Number:
- 202-448-4
- EC Name:
- 3,4-dichloroaniline
- Cas Number:
- 95-76-1
- Molecular formula:
- C6H5Cl2N
- IUPAC Name:
- 3,4-dichloroaniline
- Details on test material:
- purity: no data
Constituent 1
Test organisms
- Test organisms (species):
- other: other avian: Agelaius phoenicus
Results and discussion
Effect levelsopen allclose all
- Duration (if not single dose):
- 18 h
- Dose descriptor:
- LD50
- Effect level:
- 237 mg/kg bw
- Basis for effect:
- mortality
- Dose descriptor:
- other: R50
- Effect level:
- 0.316 other: mg/0.1 g food
- Conc. / dose based on:
- test mat.
- Basis for effect:
- repellency
- Remarks on result:
- other: 1.58 mg/feeding
- Dose descriptor:
- other: R50
- Effect level:
- 24.6 mg/kg bw
- Conc. / dose based on:
- test mat.
- Basis for effect:
- repellency
- Remarks on result:
- other: calculated value
Any other information on results incl. tables
For 3,4-DCA a short-term investigation with birds determining the acute lethal effect
after oral application is available. After 18 hours a LD50 of 237 mg/kg bw/day for Red-winged
Black birds were obtained. 3,4-DCA was usually dosed by gavage with solutions or suspensions
in propylene glycol (Schafer et al., 1983). This study cannot be used for the assessment.
Applicant's summary and conclusion
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