Registration Dossier
Registration Dossier
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EC number: 202-448-4 | CAS number: 95-76-1
Long-term toxicity to aquatic invertebrates
Administrative data
- Endpoint:
- long-term toxicity to aquatic invertebrates
- Type of information:
- experimental study
- Adequacy of study:
- other information
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Peer reviewed in EU-Risk Assessment, original data not available.
Data source
Referenceopen allclose all
- Reference Type:
- secondary source
- Title:
- 3,4-dichloroaniline (3,4-DCA)
- Author:
- EU-Risk Assessment Report
- Year:
- 2 006
- Bibliographic source:
- EUR 22235 EN; ISSN 1018-5593
- Reference Type:
- publication
- Title:
- Metier (Modular ecotoxicity tests incooperating ecological relevance) for difficult substances. 4. Test chamber for Cladocerans in flow-through conditions.
- Author:
- Diamantino T, Ribero R, Goncalves F and Soares AMVM
- Year:
- 1 997
- Bibliographic source:
- Environmental Toxicology and Chemistry 16 (6), m1234-1238
Materials and methods
- GLP compliance:
- not specified
Test material
- Reference substance name:
- 3,4-dichloroaniline
- EC Number:
- 202-448-4
- EC Name:
- 3,4-dichloroaniline
- Cas Number:
- 95-76-1
- Molecular formula:
- C6H5Cl2N
- IUPAC Name:
- 3,4-dichloroaniline
Constituent 1
Sampling and analysis
- Analytical monitoring:
- not specified
Test organisms
- Test organisms (species):
- Daphnia magna
Study design
- Test type:
- other: semi-static and flow through
- Water media type:
- freshwater
- Limit test:
- no
- Total exposure duration:
- 14 d
Results and discussion
Effect concentrationsopen allclose all
- Duration:
- 14 d
- Dose descriptor:
- NOEC
- Effect conc.:
- 0.003 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- reproduction
- Remarks on result:
- other: Semi-static with offspring
- Duration:
- 14 d
- Dose descriptor:
- NOEC
- Effect conc.:
- 0.005 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- reproduction
- Remarks on result:
- other: flow-through with offspring
Any other information on results incl. tables
Results from differnd test designs:
Semi-Static:
14-day NOEC = 0.025 mg/l c)
14-day NOEC = 0.005 mg/l d)
14-day NOEC = 0.0025 mg/l e)
(Effect: c) first batch of eggs in the brood pouch, d) aborted eggs, e) offspring; semistatic:
renewal after 48 h; nominal concentration)
Flow-Though:
14-day NOEC = > 0.050 mg/l c)
14-day NOEC = 0.005 mg/l d)
14-day NOEC = 0.005 mg/l e)
(Effect: c) first batch of eggs in the brood pouch, d) aborted eggs, e) offspring; flow-though;
nominal concentration; closed system)
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
