Registration Dossier
Registration Dossier
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EC number: 202-448-4 | CAS number: 95-76-1
Toxicity to soil macroorganisms except arthropods
Administrative data
- Endpoint:
- toxicity to soil macroorganisms except arthropods: short-term
- Type of information:
- experimental study
- Adequacy of study:
- other information
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: peer reviewed data cited in EU risk assessment report
Data source
Referenceopen allclose all
- Reference Type:
- publication
- Title:
- No information
- Author:
- van Gestel, van Dis
- Year:
- 1 988
- Bibliographic source:
- Biol. Fertil. Soils 6, 262-265
- Reference Type:
- secondary source
- Title:
- 3,4-dichloroaniline (3,4-DCA)
- Author:
- EU-Risk Assessment Report
- Year:
- 2 006
- Bibliographic source:
- EUR 22235 EN; ISSN 1018-5593
- Reference Type:
- review article or handbook
- Title:
- 2,4-Dichloranilin; 2,5-Dichloranilin; 3,4-Dichloranilin
- Author:
- Beratergremium für umweltrelevante Altstoffe (BUA)
- Year:
- 1 994
- Bibliographic source:
- Wissenschaftliche Verlagsgesellschaft, BUA report 140
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 207 (Earthworm, Acute Toxicity Tests)
- Deviations:
- yes
- Remarks:
- natural sandy soil used
- GLP compliance:
- not specified
Test material
- Reference substance name:
- 3,4-dichloroaniline
- EC Number:
- 202-448-4
- EC Name:
- 3,4-dichloroaniline
- Cas Number:
- 95-76-1
- Molecular formula:
- C6H5Cl2N
- IUPAC Name:
- 3,4-dichloroaniline
Constituent 1
Test organisms
- Test organisms (species):
- Eisenia fetida
- Animal group:
- annelids
- Details on test organisms:
- Eisenia fetida andrei
Study design
- Study type:
- laboratory study
- Substrate type:
- natural soil
- Total exposure duration:
- 14 d
Test conditions
- Test temperature:
- 23 +/- 2 °C
- pH:
- test 1: adjusted to pH 7
test 2: natural pH of 4.1 - Details on test conditions:
- natural sandy soil with a soil organic matter content of 1.7%
12h light/ 12 h darkness
Results and discussion
Effect concentrationsopen allclose all
- Duration:
- 7 d
- Dose descriptor:
- LC50
- Effect conc.:
- 130 mg/kg soil dw
- Nominal / measured:
- nominal
- Basis for effect:
- mortality
- Remarks on result:
- other: for pH 7 and 4.1; > 100 < 180 mg/kg soil dw
- Duration:
- 14 h
- Dose descriptor:
- LC50
- Effect conc.:
- 130 mg/kg soil dw
- Nominal / measured:
- nominal
- Basis for effect:
- mortality
- Remarks on result:
- other: for pH 7 and 4.1; > 100 < 180 mg/kg soil dw
- Details on results:
- no exact LC50 could be determined due to a very steep dose-response-relationship
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
