Registration Dossier
Registration Dossier
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EC number: 402-810-3 | CAS number: 17980-47-1 DYNASILAN BH N; DYNASILAN BSM 100 N; DYNASILAN NH 42
Toxicological Summary
Administrative data
Workers - Hazard via inhalation route
Systemic effects
Acute/short term exposure
DNEL related information
Local effects
Acute/short term exposure
DNEL related information
Workers - Hazard via dermal route
Systemic effects
Acute/short term exposure
DNEL related information
Workers - Hazard for the eyes
Additional information - workers
Isobutyltriethoxysilane is not hazardous for human health with respect to acute toxicity (lethality or specific target organ toxicity following a single exposure), sensitisation, specific target organ toxicity following repeated exposures, reproductive toxicity, developmental toxicity, carcinogenicity and genetic toxicity.
In the absence of adverse effects in acute and long-term systemic and reproductive studies it is not possible to determine DNEL values for systemic effects and quantitative risk characterisation is not necessary.
The critical health effect is skin irritation, for which no quantitative dose descriptors are available. Qualitative risk characterisation is therefore performed for this endpoint.
General Population - Hazard via inhalation route
Systemic effects
Acute/short term exposure
DNEL related information
Local effects
Acute/short term exposure
DNEL related information
General Population - Hazard via dermal route
Systemic effects
Acute/short term exposure
DNEL related information
General Population - Hazard via oral route
Systemic effects
Acute/short term exposure
DNEL related information
General Population - Hazard for the eyes
Additional information - General Population
Isobutyltriethoxysilane is not hazardous for human health with respect to acute toxicity (lethality or specific target organ toxicity following a single exposure), sensitisation, specific target organ toxicity following repeated exposures, reproductive toxicity, developmental toxicity, carcinogenicity and genetic toxicity.
In the absence of adverse effects in acute and long-term systemic and reproductive studies it is not possible to determine DNEL values for systemic effects and quantitative risk characterisation is not necessary.
The critical health effect is skin irritation, for which no quantitative dose descriptors are available. Qualitative risk characterisation is therefore performed for this endpoint.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
