Registration Dossier
Registration Dossier
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EC number: 456-830-2 | CAS number: 745070-61-5
Endpoint summary
Administrative data
Key value for chemical safety assessment
Effects on fertility
Additional information
No fertility studies were performed. However, oral repeated-dose studies up to 90 days of treatment did not give any indication that reproductive organs were affected by the test article administration.
Short description of key information:
From repeated dose toxicity studies it is concluded that the test substance does not adversely affect fertility.
Effects on developmental toxicity
Description of key information
From repeated dose toxicity studies it is suggested that the test substance does not adversely affect reproduction and development. In these studies the absence of any adverse findings indicate that the bioavailability of the test substance is neglectable and does therefore not induce any systemic toxicity.
Additional information
No studies on developmental toxicity were performed. However, oral repeated dose studies up to 90 days of treatment did not give any indication that reproductive performance or development might be affected by the test article administration.
Justification for classification or non-classification
There is no evidence that classification of the test item with regard to toxicity to reproduction is indicated.
The test item is not classified for this endpoint in accordance with Directive 67/548/EEC or with the CLP Regulation (EC) No 1272/2008 reflecting GHS regulations.
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
