Registration Dossier
Registration Dossier
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EC number: 282-208-3 | CAS number: 84144-87-6 Flue dust and ash containing vanadium resulting from the combustion of vanadium-bearing fuel oil.
Endpoint summary
Administrative data
Key value for chemical safety assessment
Additional information
In a reverse gene mutation assay in bacteria according to OECD 471, four strains of S. typhimurium (TA98, TA100, TA1535, TA1537) and one strain of E. coli (WP2 uvrA pKM101) were exposed to Vanadium concentrate at concentrations of 5, 1.6, 0.5, 0.16, 0.05 mg/plate in the presence and absence of mammalian metabolic activation. Vanadium concentrate was tested up to the limit concentration (5 mg/plate). The positive controls induced the appropriate responses in the corresponding strains.
Short description of key information:
The mutagenic potential of the test material was assessed in a bacterial reverse mutation assay according to OECD 471 (Chelab 2010d).
Endpoint Conclusion: No adverse effect observed (negative)
Justification for classification or non-classification
There was no evidence or a concentration related positive response of induced mutant colonies over background.
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