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Physical & Chemical properties

Water solubility

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Reference
Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2012-02-15 to 2012-02-22
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
EU Method A.6 (Water Solubility)
GLP compliance:
no
Type of method:
column elution method
Key result
Water solubility:
< 0.15 mg/L
Conc. based on:
test mat.
Loading of aqueous phase:
6.84 g/L
Incubation duration:
2 h
Temp.:
20 °C
pH:
> 6.3 - < 6.7

Table 1: Quantitative determination of the analyte

Flow rate (mL/h)

Fraction No.

Water solubility (mg/L)

pH value

25.0

1 (1-2)

< 0.15

6.7

2 (3-4)

< 0.15

6.6

3 (5-6)

<0.15

6.5

4 (7-8)

<0.15

6.5

5 (9-10)

<0.15

6.4

6 (11-12)

< 0.15

6.5

7(13-14)

< 0.15

6.4

8 (15-16)

< 0.15

6.5

12.5

1 (1-2)

< 0.15

6.5

2 (3-4)

<0.15

6.3

3 (5-6)

< 0.15

6.4

4 (7-8)

< 0.15

6.4

5(9-10)

< 0.15

6.4

6(11-12)

<0.15

6.3

7 (13-14)

<0.15

6.3

8(15-16)

<0.15

6.3

Conclusions:
The water solubility was determined to be below 0.15 mg/L at 20 °C
Executive summary:

The water solubility of the test item was determined according to EU test method L142 A/57-66 (EEC A.6). The water solubility was determined to be below 0.15 mg/L at 20 °C. The pH value of the collected aqueous fractions varied from 6.3 to 6.7.

Description of key information

The water solubility was determined to be below 0.15 mg/L at 20 °C.

Key value for chemical safety assessment

Additional information

The water solubility of the test item was determined according to EU test method L142 A/57-66 (EEC A.6). The water solubility was determined to be below 0.15 mg/L at 20 °C. The pH value of the collected aqueous fractions varied from 6.3 to 6.7.